Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | PHGDH | O43175 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15291858 | 0.84 | HRH3 (0.51) | HRH3DPP4DPP9DPP7DRD2 | |
| Hydrochloric Acid SCHEMBL3331239 | 0.82 | HRH3 (0.52) | HRH3DRD2DRD3PHGDHHTR1A | |
| SCHEMBL18901695 | 0.81 | PKM (0.53) | CCR2KCNH2CCR5 | |
| SCHEMBL18544728 | 0.80 | HRH3 (0.53) | HRH3DPP4DPP9DPP7DRD2 | |
| SCHEMBL4322431 | 0.80 | CCR2 (0.53) | HRH3DPP4DPP9DPP7DRD2 | |
| SCHEMBL28773706 | 0.78 | HRH3 (0.55) | HRH3DPP4DPP9DPP7DRD2 | |
| SCHEMBL3859907 | 0.77 | HRH3 (0.51) | HRH3DGAT2POLBACACBCCR2 | |
| SCHEMBL18901634 | 0.77 | MAPT (0.50) | HRH3DPP4DPP7POLBCCR2 | |
| SCHEMBL1351805 | 0.76 | HTR3E (0.60) | HRH3DPP4DPP9DPP7DRD2 | |
| SCHEMBL31381344 | 0.76 | KDM4E (0.57) | HRH3DPP4DPP9DPP7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |