Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.51 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901428 | 0.84 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL18901708 | 0.84 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL18901839 | 0.84 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL18901675 | 0.80 | CCR2 (0.69) | CCR2KCNH2CCR5 | |
| SCHEMBL18901573 | 0.79 | CCR2 (0.46) | CCR2KCNH2CCR5 | |
| SCHEMBL18901530 | 0.78 | SYK (0.49) | CCR2KCNH2CCR5 | |
| SCHEMBL18901429 | 0.75 | SYK (0.49) | CCR2KCNH2CCR5 | |
| SCHEMBL18544404 | 0.71 | HRH3 (0.54) | CCR2KCNH2 | |
| SCHEMBL13335007 | 0.71 | CCR2 (0.83) | CCR2KCNH2CCR5 | |
| SCHEMBL13335051 | 0.71 | CCR2 (0.83) | CCR2KCNH2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |