Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544404 | 0.81 | HRH3 (0.54) | MAPTHRH3FFAR4ADRB1TRPV1 | |
| SCHEMBL18901429 | 0.80 | SYK (0.49) | MAPTHRH3TRPV1CCR2KDM4E | |
| SCHEMBL27747094 | 0.78 | ADRB1 (0.62) | MAPTHRH3FFAR4ADRB1TRPV1 | |
| SCHEMBL18901695 | 0.78 | PKM (0.53) | ADRB1CCR2KDM4EALDH1A1LMNA | |
| SCHEMBL18901682 | 0.78 | POLB (0.51) | TRPV1POLBCCR2LMNAKCNH2 | |
| SCHEMBL1350579 | 0.77 | ADRB1 (0.64) | MAPTHRH3FFAR4ADRB1DPP4 | |
| SCHEMBL18901699 | 0.77 | HRH3 (0.49) | HRH3POLBDPP4DPP7CCR2 | |
| Trifluoroacetic Acid SCHEMBL4155295 | 0.77 | POLB (0.67) | MAPTPOLBALDH1A1LMNA | |
| SCHEMBL7134998 | 0.77 | KDM4E (0.67) | MAPTHRH3FFAR4ADRB1DPP4 | |
| SCHEMBL18901821 | 0.76 | TRPV1 (0.39) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |