Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.58 |
| ▸ | ERN1 | O75460 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897461 | 0.84 | ESR1 (0.51) | MIFERN1ESR1ESR2 | |
| SCHEMBL1647149 | 0.82 | ERN1 (0.52) | MIFERN1ESR1ESR2ALDH5A1 | |
| SCHEMBL27924236 | 0.82 | MIF (0.50) | MIFERN1ESR1ESR2SIRT1 | |
| SCHEMBL12432307 | 0.79 | ESR1 (0.48) | MIFESR1ESR2 | |
| SCHEMBL7913737 | 0.78 | TRIM24 (0.47) | MIFERN1ESR1ESR2TRIM24 | |
| SCHEMBL29952866 | 0.78 | TRIM24 (0.47) | MIFERN1ESR1ESR2TRIM24 | |
| SCHEMBL662597 | 0.77 | MIF (0.53) | MIFESR1ESR2SIRT1TTR | |
| SCHEMBL18664018 | 0.77 | MIF (0.53) | MIFESR1ESR2SIRT1TYR | |
| SCHEMBL3718412 | 0.77 | APP (0.51) | MIFERN1TRIM24TYRTRIM33 | |
| SCHEMBL93513 | 0.76 | TYR (0.61) | TRIM24TYRTRIM33TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059887-A | Synthesis method of 4-difluoromethoxy-1-difluoromethyl-2-fluorobenzene | 埃法姆(常州)生命科学技术有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-115124410-B | Preparation method of 2-fluoro-4-hydroxybenzaldehyde | 上海珂华生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117820095-A | Process method for synthesizing 2-fluoro-4-hydroxybenzaldehyde | 大连双硼医药化工有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-112574396-B | 2-fluorophenyl fluorene and pyrrolo-pyrrole-dione copolymer photovoltaic material, preparation method and application | 湖南文理学院 | 2023-11-03 | — | — | CN | claimed |
| CN-115124410-A | Preparation method of 2-fluoro-4-hydroxybenzaldehyde | 上海珂华生物科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-112574396-A | 2-fluorophenyl fluorene and pyrrolopyrroledione copolymer photovoltaic material, preparation method and application | 湖南文理学院 | 2021-03-30 | — | — | CN | claimed |
| CN-110423487-A | A kind of Rhodol derivative dye and its application | UNIV HUNAN | 2019-11-08 | — | — | CN | claimed |
| CN-110183328-A | One kind diene monomers containing carboxylate structure and its polyester and sulfur-bearing polyester | 贵州大学 | 2019-08-30 | — | — | CN | claimed |
| CN-104211682-B | Pyridine compounds and their and application thereof | 沈阳药科大学 | 2017-06-06 | — | — | CN | claimed |
| CN-104211682-A | pyridine compounds and applications thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-12-17 | — | — | CN | claimed |
| CN-1589136-A | Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups | CUTANIX CORP (US) | 2005-03-02 | — | — | CN | claimed |
| US-12629367-B2 | Five-membered ring-fused six-membered ring compound, preparation method therefor, and pharmaceutical composition and use thereof | HANGZHOU POLYMED BIOPHARMACEUTICALS, INC. (CN) | 2026-05-19 | — | — | US | disclosed |
| EP-3710428-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4696691-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Huilun Pharmaceutical Co., Ltd. (CN) | 2026-02-18 | — | — | EP | disclosed |
| CN-117820095-B | Process method for synthesizing 2-fluoro-4-hydroxybenzaldehyde | 大连双硼医药化工有限公司 | 2026-02-17 | — | — | CN | disclosed |
| US-20040242654-A1 | Diaryl ether derivative, addition salt thereof, and immunosuppressant | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| CN-1543451-A | Receptor modulators activated by peroxizonal proliferators (ppar) | — | 2004-11-03 | — | — | CN | disclosed |
| EP-1431275-A1 | DIARYL ETHER DERIVATIVE, ADDITION SALT THEREOF, AND IMMUNOSUPPRESSANT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629367-B2 | Five-membered ring-fused six-membered ring compound, preparation method therefor, and pharmaceutical composition and use thereof | IRAK4, IRAK1, IRAK2 | MIF 278/4885ERN1 983/4885ESR1 2227/4885 |
| US-20040242654-A1 | Diaryl ether derivative, addition salt thereof, and immunosuppressant | IL2, TSLP, HLA-DRB1 | MIF 318/4885ERN1 3951/4885ESR1 4013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.