Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902056 | 0.81 | KDM4E (0.35) | TRPV1KDM4ELMNAGAAGPR55 | |
| SCHEMBL18901965 | 0.81 | LMNA (0.36) | LMNA | |
| SCHEMBL18902111 | 0.78 | GPR119 (0.48) | — | |
| SCHEMBL20124509 | 0.74 | ACACB (0.36) | TRPV1KDM4EACACB | |
| SCHEMBL18901952 | 0.72 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL14406328 | 0.71 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL14935790 | 0.70 | TRPV1 (0.35) | TRPV1LMNAKCNH2 | |
| SCHEMBL12074542 | 0.70 | TRPV1 (0.35) | TRPV1LMNAKCNH2 | |
| SCHEMBL12074068 | 0.70 | TRPV1 (0.35) | TRPV1LMNAKCNH2 | |
| SCHEMBL12074313 | 0.69 | GPR119 (0.46) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173411-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | Purdue Pharma L.P. (US) | 2017-05-31 | — | — | EP | disclosed |