Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PGD | P52209 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259228 | 1.00 | ADAM17 (0.33) | ADAM17ALDH1A1TSHRPGD | |
| SCHEMBL713247 | 0.86 | ALDH1A1 (0.39) | ADAM17ALDH1A1TSHR | |
| SCHEMBL283357 | 0.86 | ALDH1A1 (0.39) | ADAM17ALDH1A1TSHR | |
| SCHEMBL2832006 | 0.86 | ALDH1A1 (0.39) | ADAM17ALDH1A1TSHR | |
| SCHEMBL2832987 | 0.86 | ALDH1A1 (0.39) | ADAM17ALDH1A1TSHR | |
| SCHEMBL77247 | 0.76 | LMNA (0.42) | ALDH1A1TSHRPGD | |
| SCHEMBL7093505 | 0.76 | LMNA (0.42) | ALDH1A1TSHRPGD | |
| SCHEMBL1874716 | 0.76 | LMNA (0.42) | ALDH1A1TSHRPGD | |
| SCHEMBL3072719 | 0.76 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL11339365 | 0.76 | TSHR (0.56) | ADAM17ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173408-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | Taisho Pharmaceutical Co., Ltd. (JP) | 2017-05-31 | — | — | EP | disclosed |