SCHEMBL7259228

SCHEMBL7259228

CN(C)C(=O)C(O)C(O)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADAM17 P78536 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
PGD P52209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18902855 1.00 ADAM17 (0.33) ADAM17ALDH1A1TSHRPGD
SCHEMBL713247 0.86 ALDH1A1 (0.39) ADAM17ALDH1A1TSHR
SCHEMBL283357 0.86 ALDH1A1 (0.39) ADAM17ALDH1A1TSHR
SCHEMBL2832006 0.86 ALDH1A1 (0.39) ADAM17ALDH1A1TSHR
SCHEMBL2832987 0.86 ALDH1A1 (0.39) ADAM17ALDH1A1TSHR
SCHEMBL77247 0.76 LMNA (0.42) ALDH1A1TSHRPGD
SCHEMBL7093505 0.76 LMNA (0.42) ALDH1A1TSHRPGD
SCHEMBL1874716 0.76 LMNA (0.42) ALDH1A1TSHRPGD
SCHEMBL3072719 0.76 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL11339365 0.76 TSHR (0.56) ADAM17ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6642170-B1 Metals selected from tantalum, vanadium, niobium, chromium, molybdenum or tungsten on catalyst supports such as zeolites, oxides of silicon, aluminum, titanium, titanium, niobium or tantalum, used for etherification of alcohols-2+ CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2003-11-04 US claimed
US-6642170-B1 Metals selected from tantalum, vanadium, niobium, chromium, molybdenum or tungsten on catalyst supports such as zeolites, oxides of silicon, aluminum, titanium, titanium, niobium or tantalum, used for etherification of alcohols-2+ CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2003-11-04 US disclosed
US-5245046-A α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents THE UPJOHN COMPANY (US) 1993-09-14 US disclosed
US-5173112-A Nonplugging, improved storage stability E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-22 US disclosed
US-5166371-A Catalytic epoxidation of allyl alcohol using a hydroperoxide ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1992-11-24 US disclosed
EP-0472790-A1 Asymmetric epoxidation using a chiral hydroperoxide ARCO Chemical Technology, L.P. (US) 1992-03-04 EP disclosed
WO-1990005721-A1 ALPHA-AMINO-INDOLE-3-ACETIC ACIDS USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS THE UPJOHN COMPANY (US) 1990-05-31 WO disclosed
US-4594439-A Resolution of chiral carbinol having aliphatic unsaturation THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) 1986-06-10 US disclosed
US-4471130-A SELECTIVE STEREOISOMERS BY REACTING AN ALKENOL AND HYDROPEROXIDE USING A TRANSITION METAL ALKOKIDE CATALYST THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1984-09-11 US disclosed