SCHEMBL18904333

SCHEMBL18904333

C[Si]1(C)c2ccccc2-c2cc3c(-c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccc6c7c(cccc57)-c5ccccc5-6)cc4c(-c4ccc(-c5ccccc5)cc4)c3cc21

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ RORA P35398 1/20 0.31
▸ RORC P51449 1/20 0.31
▸ CRHBP P24387 1/20 0.30
▸ CRHR2 Q13324 1/20 0.30
▸ KEAP1 Q14145 1/20 0.30
▸ NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18903099 0.94 CRHBP (0.32) CRHBPCRHR2KEAP1NFE2L2
SCHEMBL18904335 0.92 L3MBTL1 (0.32) RORARORCCRHBPCRHR2KEAP1
SCHEMBL18904338 0.92 RORA (0.33) RORARORCCRHBPCRHR2KEAP1
SCHEMBL18904334 0.91 RORA (0.31) RORARORCCRHBPCRHR2KEAP1
SCHEMBL18902896 0.90 — —
SCHEMBL18904327 0.88 MCL1 (0.37) RORARORC
SCHEMBL12796277 0.88 ALDH1A1 (0.33) —
SCHEMBL18904329 0.88 ALDH1A1 (0.34) RORARORC
SCHEMBL18904331 0.87 RORA (0.35) RORARORC
SCHEMBL18904385 0.87 RORA (0.37) RORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10720473-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-21 — — US disclosed
US-20190296091-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 — — US disclosed
US-10361252-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 — — US disclosed
US-20180040827-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-08 — — US disclosed
US-20180040827-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-08 — — US disclosed
US-20170154931-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
US-20170154931-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
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