SCHEMBL18904379

SCHEMBL18904379

C[Si]1(C)c2cc(-c3ccc4c5c(cccc35)-c3ccccc3-4)ccc2-c2cc3c(-c4ccc5c6c(cccc46)-c4ccccc4-5)c4ccccc4c(-c4ccc5c6c(cccc46)-c4ccccc4-5)c3cc21

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CRHBP P24387 1/20 0.34
▸ CRHR2 Q13324 1/20 0.34
▸ KEAP1 Q14145 1/20 0.34
▸ NFE2L2 Q16236 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ PABPC1 P11940 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HKDC1 Q2TB90 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18904366 0.95 ALDH1A1 (0.36) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904361 0.94 CRHBP (0.32) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904338 0.94 RORA (0.33) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL13304269 0.93 ALDH1A1 (0.35) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904368 0.92 L3MBTL1 (0.34) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904380 0.92 ALDH1A1 (0.37) ALDH1A1HPGDTSHRMAPK1CASP1
SCHEMBL18903099 0.91 CRHBP (0.32) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904376 0.91 L3MBTL1 (0.33) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904374 0.91 ALDH1A1 (0.43) CRHBPCRHR2KEAP1NFE2L2ALDH1A1
SCHEMBL18904329 0.90 ALDH1A1 (0.34) ALDH1A1HPGDTSHRMAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10720473-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-21 — — US disclosed
US-20190296091-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 — — US disclosed
US-10361252-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 — — US disclosed
US-20180040827-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-08 — — US disclosed
US-20180040827-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-08 — — US disclosed
US-20170154931-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
US-20170154931-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
Send feedback