Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905262 | 0.85 | MEN1 (0.46) | ALDH1A1TSHRMEN1KMT2AAOC3 | |
| SCHEMBL6055121 | 0.84 | NQO1 (0.58) | LMNATSHRMEN1KMT2ANQO1 | |
| SCHEMBL18905524 | 0.84 | LMNA (0.46) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9499186 | 0.81 | LTA4H (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL9498777 | 0.81 | LTA4H (0.52) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18905256 | 0.80 | ALDH1A1 (0.40) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9499961 | 0.79 | NQO1 (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL21910441 | 0.79 | PARP15 (0.49) | LMNAFFAR1 | |
| SCHEMBL1607138 | 0.78 | LMNA (0.75) | LMNAALDH1A1TSHRAOC3TAAR1 | |
| SCHEMBL9498490 | 0.78 | NR5A1 (0.58) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |