SCHEMBL18905451

SCHEMBL18905451

OC1(c2cccc([SiH3])c2)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.36
OPRK1 P41145 6/20 0.36
OPRL1 P41146 6/20 0.36
OPRD1 P41143 4/20 0.36
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
AKR1C1 Q04828 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SYK P43405 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905270 0.98 OPRM1 (0.36) OPRM1OPRK1OPRL1OPRD1CYP4F2
SCHEMBL18905296 0.77 SLC6A4 (0.37) SLC6A2SLC6A4KMT2A
SCHEMBL2718795 0.76 CYP3A4 (0.42) OPRM1OPRK1OPRL1OPRD1ALDH1A1
SCHEMBL27681431 0.76 SLC6A4 (0.54) OPRM1OPRK1OPRL1OPRD1SLC6A2
SCHEMBL27266340 0.76 OPRM1 (0.56) OPRM1OPRK1OPRL1OPRD1SLC6A2
SCHEMBL17982783 0.76 OPRL1 (0.56) OPRM1OPRK1OPRL1OPRD1SLC6A2
SCHEMBL1598944 0.76 OPRL1 (0.36) OPRM1OPRK1OPRL1OPRD1CYP4F2
SCHEMBL3946783 0.76 OPRM1 (0.47) OPRM1OPRK1OPRD1SLC6A2SLC6A4
SCHEMBL7136098 0.76 ALDH1A1 (0.42) OPRM1OPRK1OPRL1OPRD1SLC6A2
SCHEMBL18905264 0.76 SLC6A4 (0.39) SLC6A2SLC6A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170154766-A1 SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-06-01 US disclosed