Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475863 | 0.82 | ESR1 (0.57) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL9219871 | 0.81 | OPRD1 (0.44) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL6681808 | 0.81 | DRD2 (0.50) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| Hydrochloric Acid SCHEMBL31690834 | 0.79 | DRD2 (0.49) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL612783 | 0.79 | MEN1 (0.44) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL3084744 | 0.79 | OPRM1 (0.43) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL1154800 | 0.78 | SLC6A4 (0.57) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL971031 | 0.78 | SMN1; SMN2 (0.41) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 | |
| SCHEMBL18905270 | 0.78 | OPRM1 (0.36) | OPRM1SLC6A4OPRD1OPRK1 | |
| SCHEMBL15823214 | 0.78 | SMN1; SMN2 (0.41) | OPRM1SLC6A4OPRD1SLC6A2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| EP-2668152-B1 | BICYCLIC TRAMADOL DERIVATIVES FOR CONTROLLING PAIN | LILLY CO ELI (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2009018169-A1 | SUBSTITUTED CYCLOHEXANOLS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008151156-A1 | PHENYL SUBSTITUTED CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2008-12-11 | — | — | WO | disclosed |