Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911294 | 0.88 | POLB (0.41) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL17047614 | 0.88 | POLB (0.44) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL18905592 | 0.83 | CYP1A2 (0.41) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL17047630 | 0.83 | POLB (0.38) | POLBSMN1; SMN2ALDH1A1CYP1A2GAA | |
| SCHEMBL2354099 | 0.81 | CYP1A2 (0.42) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL8231853 | 0.80 | ALDH1A1 (0.44) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL17072529 | 0.79 | ALDH1A1 (0.42) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL15743383 | 0.79 | ALDH1A1 (0.42) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL18905595 | 0.77 | ALOX15 (0.38) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 | |
| SCHEMBL17047634 | 0.75 | ALOX15 (0.36) | POLBSMN1; SMN2ALDH1A1TRPA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152274-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | PHOSPHO1, PCTP, CD2BP2 | POLB 3395/4885SMN1; SMN2 3710/4885ALDH1A1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.