Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890693 | 0.84 | FOLH1 (0.35) | — | |
| Phosphoramidic Acid SCHEMBL13280710 | 0.82 | FOLH1 (0.34) | — | |
| Phosphoramidic Acid SCHEMBL1691899 | 0.82 | FOLH1 (0.34) | — | |
| SCHEMBL771737 | 0.82 | CA4 (0.39) | — | |
| SCHEMBL9807834 | 0.82 | CA4 (0.39) | — | |
| SCHEMBL29057791 | 0.76 | CA4 (0.39) | — | |
| Pyrophosphoric Acid SCHEMBL29046521 | 0.75 | FDPS (0.32) | — | |
| SCHEMBL28292794 | 0.71 | CA4 (0.33) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19347953 | 0.70 | LAP3 (0.37) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28364307 | 0.70 | LAP3 (0.37) | CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158197-A2 | COMPOUNDS USEFUL AS AKT/PKB MODULATORS AND USES THEREOF | LYNDOR BIOSCIENCES L.L.C. (US) | 2012-11-22 | — | — | WO | claimed |
| WO-2011133212-A1 | METHODS, COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING ANXIETY AND MOOD DISORDERS | NEW YORK UNIVERSITY (US) | 2011-10-27 | — | — | WO | claimed |
| WO-2008121941-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TSRL, INC. (US) | 2008-10-09 | — | — | WO | claimed |
| WO-2012158197-A2 | COMPOUNDS USEFUL AS AKT/PKB MODULATORS AND USES THEREOF | LYNDOR BIOSCIENCES L.L.C. (US) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012142388-A2 | METHODS, COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING ANXIETY AND MOOD DISORDERS | NEW YORK UNIVERSITY (US) | 2012-10-18 | — | — | WO | disclosed |
| US-8242087-B2 | Phosphate modified nucleosides useful as substrates for polymerases and as antiviral agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-08-14 | — | — | US | disclosed |
| WO-2011133212-A1 | METHODS, COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING ANXIETY AND MOOD DISORDERS | NEW YORK UNIVERSITY (US) | 2011-10-27 | — | — | WO | disclosed |
| US-20110112046-A9 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-05-12 | — | — | US | disclosed |
| US-20100093656-A1 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2010-04-15 | — | — | US | disclosed |
| EP-2144921-A2 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K.U. Leuven Research and Development (BE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008121941-A1 | PRODRUGS OF TRICIRIBINE AND TRICIRIBINE PHOSPHATE | TSRL, INC. (US) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008104408-A2 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | K. U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112046-A9 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | MTAP, POLRMT, PNP | CYP2D6 3715/4885CYP2C9 4379/4885CYP2C19 4582/4885 |
| US-20100093656-A1 | PHOSPHATE MODIFIED NUCLEOSIDES USEFUL AS SUBSTRATES FOR POLYMERASES AND AS ANTIVIRAL AGENTS | MTAP, POLRMT, PNP | CYP2D6 3715/4885CYP2C9 4379/4885CYP2C19 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.