Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207015 | 0.82 | NAAA (0.64) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL24856036 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1HPGDHDAC3HDAC1 | |
| SCHEMBL10587847 | 0.80 | ALDH1A1 (0.83) | SMN1; SMN2ALDH1A1EPHX1HPGDHDAC3 | |
| SCHEMBL31069913 | 0.80 | NAAA (0.66) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL7568980 | 0.80 | NAAA (0.66) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL258780 | 0.80 | NAAA (0.66) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL19232285 | 0.80 | NAAA (0.54) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL28448079 | 0.78 | NAAA (0.59) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL3473161 | 0.75 | NAAA (0.56) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA | |
| SCHEMBL31302650 | 0.75 | NAAA (0.59) | SMN1; SMN2ALDH1A1EPHX1HPGDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190085034-A1 | ANTIBODY MIMIC CONJUGATES AND PARTICLES | TVA (ABC), LLC | 2019-03-21 | — | — | US | disclosed |
| US-20180021454-A1 | TARGETED CONJUGATES ENCAPSULATED IN PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2018-01-25 | — | — | US | disclosed |
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190085034-A1 | ANTIBODY MIMIC CONJUGATES AND PARTICLES | CD47, FCGR3B, FCGR2A | SMN1; SMN2 1681/4885ALDH1A1 1521/4885EPHX1 2423/4885 |
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | CD47, CD44, FURIN | SMN1; SMN2 1057/4885ALDH1A1 1159/4885EPHX1 936/4885 |
| US-20180021454-A1 | TARGETED CONJUGATES ENCAPSULATED IN PARTICLES AND FORMULATIONS THEREOF | CD47, CD44, FURIN | SMN1; SMN2 946/4885ALDH1A1 1211/4885EPHX1 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.