SCHEMBL18911384

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	2/20	0.43

▸	OPRD1	P41143	2/20	0.43

▸	OPRK1	P41145	1/20	0.43

▸	CTSD	P07339	2/20	0.42

▸	ENPEP	Q07075	7/20	0.41

▸	CTSB	P07858	2/20	0.40

▸	CTSK	P43235	2/20	0.40

▸	BACE1	P56817	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18911383	1.00	OPRM1 (0.43)	OPRM1OPRD1OPRK1CTSDENPEP
SCHEMBL29912721	0.87	FURIN (0.47)	CTSDBACE1
SCHEMBL16698216	0.86	ENPEP (0.50)	CTSDENPEP
SCHEMBL16698213	0.86	ENPEP (0.50)	CTSDENPEP
SCHEMBL29644740	0.85	OPRD1 (0.40)	OPRM1OPRD1OPRK1ENPEPCTSB
SCHEMBL2193363	0.83	OPRD1 (0.56)	OPRM1OPRD1OPRK1CTSD
SCHEMBL2193357	0.83	OPRD1 (0.56)	OPRM1OPRD1OPRK1CTSD
SCHEMBL31462063	0.83	BACE1 (0.44)	OPRM1OPRD1OPRK1CTSDCTSB
SCHEMBL29608851	0.82	CTSD (0.46)	OPRM1OPRD1CTSDENPEP
SCHEMBL31670475	0.82	ENPEP (0.49)	CTSDENPEPBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9669111-B2	Device for the diagnosis of inflammatory tissues in dental applications	THOMMEN MEDICAL AG (CH)	2017-06-06	—	—	US	disclosed