Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741719 | 0.76 | GNAO1 (0.49) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| Fluoride SCHEMBL30330474 | 0.74 | GNAO1 (0.47) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| SCHEMBL15269270 | 0.72 | TRPA1 (0.39) | NAAACYP1A2SIGMAR1 | |
| SCHEMBL14380398 | 0.72 | GNAO1 (0.59) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| SCHEMBL1269251 | 0.72 | LMNA (0.43) | NAAAHRH3CYP1A2CARM1PRMT6 | |
| SCHEMBL17274384 | 0.71 | NAAA (0.81) | NAAAKCNH2SIGMAR1CARM1PRMT6 | |
| SCHEMBL24207822 | 0.71 | GNAO1 (0.53) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| SCHEMBL14393786 | 0.71 | CYP1A2 (0.46) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| SCHEMBL7739859 | 0.71 | GNAO1 (0.45) | HRH3GNAO1CHRM2CHRM4CHRM5 | |
| SCHEMBL13906105 | 0.71 | GNAO1 (0.45) | HRH3GNAO1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152222-A1 | COMPOUNDS AND METHODS FOR INHIBITING PRODUCTION OF TRIMETHYLAMINE | THE PROCTER & GAMBLE COMPANY | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152222-A1 | COMPOUNDS AND METHODS FOR INHIBITING PRODUCTION OF TRIMETHYLAMINE | CRAT, CPT1A, CPT1B | NAAA 63/4885HRH3 782/4885GNAO1 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.