Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875119 | 0.82 | KIF11 (0.44) | KCNN4KIF11L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11417864 | 0.81 | KCNN4 (0.46) | KCNN4KIF11ALDH1A1MEN1MAPT | |
| SCHEMBL14564460 | 0.78 | EPHX2 (0.50) | KCNN4HTTL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4199968 | 0.77 | KCNN4 (0.56) | KCNN4KIF11ALDH1A1MEN1MAPT | |
| SCHEMBL17916522 | 0.74 | HDAC3 (0.51) | KCNN4KIF11L3MBTL1MAPTRAB9A | |
| SCHEMBL17875124 | 0.73 | KIF11 (0.39) | KCNN4KIF11HTTALDH1A1MEN1 | |
| SCHEMBL28544425 | 0.72 | KCNN4 (0.55) | KCNN4KIF11HTTL3MBTL1ALDH1A1 | |
| SCHEMBL17916338 | 0.71 | MTNR1A (0.49) | KCNN4KIF11L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL868147 | 0.70 | EPHX2 (0.58) | L3MBTL1ALDH1A1MEN1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL10984929 | 0.70 | KCNN4 (0.48) | KCNN4KIF11HTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017089607-A1 | DERIVATIVES OF GAMMA-AMANITIN | HEIDELBERG PHARMA GMBH (DE) | 2017-06-01 | — | — | WO | disclosed |