Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875124 | 0.90 | KIF11 (0.39) | KIF11KCNN4LMNAPOLBHPGD | |
| SCHEMBL17916522 | 0.84 | HDAC3 (0.51) | KIF11KCNN4LMNAL3MBTL1POLB | |
| SCHEMBL11417864 | 0.83 | KCNN4 (0.46) | KIF11KCNN4HPGDKMT2AALDH1A1 | |
| SCHEMBL18913034 | 0.82 | KCNN4 (0.42) | KIF11KCNN4LMNAL3MBTL1HPGD | |
| SCHEMBL17916338 | 0.78 | MTNR1A (0.49) | KIF11KCNN4L3MBTL1HPGDTSHR | |
| SCHEMBL4199968 | 0.78 | KCNN4 (0.56) | KIF11KCNN4HPGDGAATSHR | |
| SCHEMBL23476147 | 0.77 | KCNN4 (0.52) | KIF11KCNN4HPGDGAATSHR | |
| SCHEMBL17916335 | 0.76 | HDAC3 (0.46) | KCNN4LMNAL3MBTL1POLBHPGD | |
| SCHEMBL17916340 | 0.76 | ALDH1A1 (0.41) | KCNN4LMNAL3MBTL1POLBHPGD | |
| SCHEMBL14564460 | 0.76 | EPHX2 (0.50) | KCNN4LMNAL3MBTL1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037097-A1 | POLYROTAXANE AND MEDICINAL COMPOSITION | National University Corporation Tokyo Medical and Dental University (JP) | 2016-06-29 | — | — | EP | disclosed |