Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | GAA | P10253 | 7/20 | 0.76 |
| ▸ | GLA | P06280 | 5/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335474 | 0.87 | KDM4E (1.00) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL29651337 | 0.87 | KDM4E (1.00) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL7917973 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL1459402 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL2534958 | 0.83 | ALDH1A1 (0.82) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL31120325 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL27788739 | 0.83 | ALDH1A1 (0.77) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL12986854 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL10867007 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL29843007 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-12-05 | — | — | US | disclosed |
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | disclosed |
| US-11998610-B2 | Conjugates and methods of using the same | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-11584752-B2 | Method for controlled release using mechanical force | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220033372-A1 | METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-02-03 | — | — | US | disclosed |
| CN-106470977-B | Water-soluble activatable molecular probe, synthetic intermediate thereof and related detection method | 里昂高等师范学院 | 2021-07-09 | — | — | CN | disclosed |
| EP-3836971-A1 | CONJUGATES AND METHODS OF USING THE SAME | Flagship Pioneering Innovations V, Inc. (US) | 2021-06-23 | — | — | EP | disclosed |
| US-11040951-B2 | Methods and compositions relating to genotoxin colibactin | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-22 | — | — | US | disclosed |
| US-20210162057-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-06-03 | — | — | US | disclosed |
| WO-2020037009-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-02-20 | — | — | WO | disclosed |
| US-20200055836-A1 | METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-02-20 | — | — | US | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2019-01-15 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179929-B2 | Water-soluble activatable molecular probes, intermediates for the synthesis thereof and associated detection methods | SI, GUSB, ABCG2 | ALDH1A1 426/4885KDM4E 4802/4885GAA 69/4885 |
| US-11998610-B2 | Conjugates and methods of using the same | CD47, CD44, CD74 | ALDH1A1 774/4885KDM4E 4256/4885GAA 197/4885 |
| US-20170159100-A1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | SI, GUSB, ABCG2 | ALDH1A1 426/4885KDM4E 4802/4885GAA 69/4885 |
| US-20220033372-A1 | METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN | CACYBP, MYCBP, CLSPN | ALDH1A1 4352/4885KDM4E 4738/4885GAA 2133/4885 |
| US-11584752-B2 | Method for controlled release using mechanical force | DYNLL2, PARP12, RUVBL2 | ALDH1A1 2079/4885KDM4E 3001/4885GAA 4343/4885 |
| US-20210162057-A1 | CONJUGATES AND METHODS OF USING THE SAME | CD47, CD44, CD74 | ALDH1A1 774/4885KDM4E 4256/4885GAA 197/4885 |
| US-20200055836-A1 | METHODS AND COMPOSITIONS RELATING TO GENOTOXIN COLIBACTIN | CACYBP, MYCBP, CLSPN | ALDH1A1 4352/4885KDM4E 4738/4885GAA 2133/4885 |
| US-11040951-B2 | Methods and compositions relating to genotoxin colibactin | CACYBP, MYCBP, CLSPN | ALDH1A1 4352/4885KDM4E 4738/4885GAA 2133/4885 |
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | CD47, CD44, CD74 | ALDH1A1 774/4885KDM4E 4256/4885GAA 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.