SCHEMBL1891797

SCHEMBL1891797

CCCCc1cc(-c2cccc(OPOc3cccc(-c4ccc(C)c(CCCC)c4)c3-c3ccc(C)c(CCCC)c3)c2-c2ccc(C)c(CCCC)c2)ccc1C

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 2/20 0.36
ELANE P08246 4/20 0.36
CTSG P08311 2/20 0.36
TLR8 Q9NR97 1/20 0.34
FPR1 P21462 4/20 0.33
ALOX5 P09917 1/20 0.33
PTGS2 P35354 1/20 0.33
APLNR P35414 3/20 0.32
CNR2 P34972 1/20 0.31
MAOA P21397 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
LTB4R Q15722 1/20 0.31
LTB4R2 Q9NPC1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891798 0.90 ELANE (0.37) SPHK2ELANECTSGTLR8FPR1
SCHEMBL1886252 0.83 ELANE (0.42) SPHK2ELANECTSGTLR8FPR1
SCHEMBL2679437 0.76 SPHK2 (0.35) SPHK2ELANECTSGTLR8ALOX5
SCHEMBL1886253 0.74 ELANE (0.43) ELANECTSGTLR8FPR1ALOX5
SCHEMBL1880864 0.74 TLR8 (0.42) TLR8PTGS2
SCHEMBL21916362 0.72 TNKS (0.46) LTB4R2
SCHEMBL6742752 0.70 PTGS2 (0.45) ELANECTSGALOX5PTGS2APLNR
SCHEMBL1881742 0.70 PTGS2 (0.43) ELANECTSGTLR8FPR1ALOX5
SCHEMBL22069113 0.69 HSD11B1 (0.45) TLR8CNR2
SCHEMBL1890044 0.68 ELANE (0.41) ELANECTSGFPR1ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed