SCHEMBL1886252

SCHEMBL1886252

CCCCCCc1cc(-c2cccc(OPOc3cccc(-c4ccc(CC)c(CCCCCC)c4)c3-c3ccc(CC)c(CCCCCC)c3)c2-c2ccc(CC)c(CCCCCC)c2)ccc1CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.42
PPARA Q07869 2/20 0.38
CTSG P08311 3/20 0.38
TLR8 Q9NR97 1/20 0.38
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
PPARG P37231 1/20 0.37
ALOX5 P09917 1/20 0.36
PTGS2 P35354 1/20 0.36
FPR1 P21462 2/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1886253 0.91 ELANE (0.43) ELANEPPARACTSGTLR8PPARG
SCHEMBL1891797 0.83 SPHK2 (0.36) ELANECTSGTLR8ALOX5PTGS2
SCHEMBL1880864 0.77 TLR8 (0.42) TLR8PTGS2KDM4EMEN1ALDH1A1
SCHEMBL3378232 0.77 ELANE (0.41) ELANEPPARACTSGNR1H2NR1H3
SCHEMBL1891798 0.74 ELANE (0.37) ELANEPPARACTSGTLR8ALOX5
SCHEMBL2854748 0.72 ELANE (0.39) ELANECTSGTLR8ICMT
SCHEMBL1890044 0.72 ELANE (0.41) ELANEPPARACTSGNR1H2NR1H3
SCHEMBL1881742 0.71 PTGS2 (0.43) ELANEPPARACTSGTLR8NR1H2
SCHEMBL4444324 0.70 THRA (0.54) PPARATLR8NR1H2NR1H3PPARG
SCHEMBL6743239 0.69 PTGS2 (0.50) PPARANR1H2NR1H3PPARGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed