SCHEMBL1886253

SCHEMBL1886253

CCCCCCc1cc(-c2cccc(OPO)c2-c2ccc(CC)c(CCCCCC)c2)ccc1CC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.43
PPARA Q07869 2/20 0.39
CTSG P08311 3/20 0.39
PPARG P37231 1/20 0.38
ALOX5 P09917 4/20 0.38
PTGS2 P35354 3/20 0.38
TLR8 Q9NR97 1/20 0.36
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
PTPN11 Q06124 1/20 0.36
TSHR P16473 2/20 0.36
ICMT O60725 2/20 0.35
FPR1 P21462 1/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
TYR P14679 1/20 0.35
ALOX15 P16050 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1886252 0.91 ELANE (0.42) ELANEPPARACTSGPPARGALOX5
SCHEMBL1891798 0.84 ELANE (0.37) ELANEPPARACTSGALOX5PTGS2
SCHEMBL1880866 0.78 RARB (0.40) PTGS2TLR8TSHRMEN1TP53
SCHEMBL3378232 0.78 ELANE (0.41) ELANEPPARACTSGPPARGALOX5
SCHEMBL1891797 0.74 SPHK2 (0.36) ELANECTSGALOX5PTGS2TLR8
SCHEMBL1890047 0.73 ELANE (0.42) ELANEPPARACTSGPPARGALOX5
SCHEMBL1997519 0.72 ALOX5 (0.39) ELANEPPARACTSGPPARGALOX5
SCHEMBL2854748 0.72 ELANE (0.39) ELANECTSGTLR8ICMTTYR
SCHEMBL1881743 0.72 PTGS2 (0.45) ELANEPPARACTSGPPARGALOX5
SCHEMBL11370128 0.72 THRA (0.55) PPARAPPARGALOX5PTGS2THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed