Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886823 | 1.00 | MAPT (0.38) | MAPTNPC1RAB9AMAPK1HTT | |
| SCHEMBL18920871 | 1.00 | MAPT (0.38) | MAPTNPC1RAB9AMAPK1HTT | |
| SCHEMBL29112208 | 0.90 | NPC1 (0.32) | MAPTNPC1RAB9AMAPK1HTT | |
| SCHEMBL13870141 | 0.87 | USP18 (0.37) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL13886822 | 0.87 | CA1 (0.35) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL13886821 | 0.86 | CA1 (0.34) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL28392156 | 0.85 | TXNRD1 (0.34) | TXNRD1DNMT1SLC6A3SMOPTGS2 | |
| SCHEMBL30382557 | 0.84 | USP18 (0.34) | MEN1KMT2ACA1CA2CA5A | |
| SCHEMBL13870140 | 0.84 | F10 (0.41) | CA1CA2CA5ACA9CA5B | |
| SCHEMBL13886925 | 0.83 | MAPT (0.55) | MAPTNPC1RAB9AMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383537-A1 | METHOD FOR PRODUCING A PLURALITY OF MEASUREMENT REGIONS ON A CHIP AND CHIP HAVING A PLURALITY OF MEASUREMENT REGIONS | Boehringer Ingelheim Vetmedica GmbH (DE) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017092875-A1 | METHOD FOR PRODUCING A PLURALITY OF MEASUREMENT REGIONS ON A CHIP AND CHIP HAVING A PLURALITY OF MEASUREMENT REGIONS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2017-06-08 | — | — | WO | disclosed |