Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528126 | 1.00 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL29400976 | 1.00 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL21146296 | 1.00 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL487202 | 0.91 | L3MBTL1 (0.63) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL17658726 | 0.91 | L3MBTL1 (0.60) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL30912341 | 0.91 | EPHX1 (0.62) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL29918287 | 0.91 | L3MBTL1 (0.63) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL487203 | 0.91 | L3MBTL1 (0.63) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| SCHEMBL17656911 | 0.89 | L3MBTL1 (0.58) | L3MBTL1MAPTALDH1A1RECQLEPHX1 | |
| Hydrochloric Acid SCHEMBL29918249 | 0.89 | L3MBTL1 (0.61) | L3MBTL1MAPTALDH1A1RECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024316-A | 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof | 南开大学 | 2023-11-10 | — | — | CN | claimed |
| EP-3383881-B1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS BV (NL) | 2019-07-31 | — | — | EP | claimed |
| US-10179797-B2 | Phosphinic peptide derivatives for use as MMP-12 inhibitors | DSM IP ASSETS B.V. (NL) | 2019-01-15 | — | — | US | claimed |
| US-20180319829-A1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS B.V. (NL) | 2018-11-08 | — | — | US | claimed |
| CN-108290912-A | Phosphinic acids peptide derivant as MMP-12 inhibitor | 帝斯曼知识产权资产管理有限公司 | 2018-07-17 | — | — | CN | claimed |
| CN-117024316-A | 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof | 南开大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-113861097-A | Synthesis method of multi-configuration 1-Boc-N-Fmoc tryptophan compound | 苏州爱玛特生物科技有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-108350028-B | Peptide macrocycles against Acinetobacter baumannii | 豪夫迈·罗氏有限公司 | 2021-12-07 | — | — | CN | disclosed |
| EP-3383881-B1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS BV (NL) | 2019-07-31 | — | — | EP | disclosed |
| US-10179797-B2 | Phosphinic peptide derivatives for use as MMP-12 inhibitors | DSM IP ASSETS B.V. (NL) | 2019-01-15 | — | — | US | disclosed |
| US-20180319829-A1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS B.V. (NL) | 2018-11-08 | — | — | US | disclosed |
| EP-3383881-A1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP Assets B.V. (NL) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017093093-A1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | DSM IP ASSETS B.V. (NL) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319829-A1 | PHOSPHINIC PEPTIDE DERIVATIVES FOR USE AS MMP-12 INHIBITORS | MMP12, MMP13, MMP11 | L3MBTL1 4005/4885MAPT 2103/4885ALDH1A1 2221/4885 |
| US-10179797-B2 | Phosphinic peptide derivatives for use as MMP-12 inhibitors | MMP12, MMP13, MMP11 | L3MBTL1 4005/4885MAPT 2103/4885ALDH1A1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.