SCHEMBL18922376

SCHEMBL18922376

CCCCCCCCC(CCCCCC)C1CC(C)(O)C1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
GPR84 Q9NQS5 3/20 0.34
FDPS P14324 3/20 0.34
SPHK1 Q9NYA1 1/20 0.34
FFAR1 O14842 1/20 0.34
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21235995 0.80 LMNA (0.34) LMNAGPR84FDPS
SCHEMBL21347099 0.79 MAPT (0.33) LMNAMAPT
SCHEMBL26081458 0.78 OPRM1 (0.37) LMNASPHK1MAPT
SCHEMBL14696390 0.74 LMNA (0.41) LMNA
SCHEMBL26828761 0.74 OPRM1 (0.37) LMNASPHK1MAPT
SCHEMBL22628412 0.74 OPRM1 (0.33) LMNASPHK1MAPT
SCHEMBL19301384 0.73 DNM1 (0.33) LMNA
SCHEMBL22548463 0.73 CA2 (0.36) GPR84FFAR1
SCHEMBL19697181 0.72 OPRM1 (0.34) LMNASPHK1MAPT
SCHEMBL25436140 0.72 CA1 (0.46) GPR84FDPSFFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9669032-B2 Enhanced treatment regimens using mTOR inhibitors INTELLIKINE LLC (US) 2017-06-06 US disclosed