Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15595187 | 1.00 | OGA (0.46) | OGAHDAC11MEN1KMT2ATACR1 | |
| SCHEMBL16978164 | 0.90 | BRD4 (0.47) | OGAMEN1KMT2ATACR1MAPT | |
| SCHEMBL20495191 | 0.89 | HDAC11 (0.47) | HDAC11SIGMAR1MAPT | |
| SCHEMBL9490686 | 0.84 | MAPT (0.57) | OGAMEN1KMT2ASIGMAR1MAPT | |
| SCHEMBL8870298 | 0.84 | MAPT (0.57) | OGAMEN1KMT2ASIGMAR1MAPT | |
| SCHEMBL8936180 | 0.84 | MAPT (0.57) | OGAMEN1KMT2ASIGMAR1MAPT | |
| SCHEMBL21166309 | 0.83 | KMT2A (0.59) | HDAC11KMT2ASIGMAR1MAPT | |
| SCHEMBL16982318 | 0.83 | CHRNB2 (0.46) | OGAMEN1KMT2ATACR1LTA4H | |
| SCHEMBL3398912 | 0.83 | CTSL (0.54) | HDAC11ALDH1A1 | |
| SCHEMBL19875824 | 0.78 | SIGMAR1 (0.52) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670195-B2 | Glycosidase inhibitors and uses thereof | ALECTOS THERAPEUTICS INC. (CA) | 2017-06-06 | — | — | US | disclosed |