Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067941 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL3718510 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL25184625 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL18922735 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL22596400 | 0.81 | ACHE (0.51) | ALDH1A1KDM4ETDP1POLBKMT2A | |
| SCHEMBL14157578 | 0.81 | TDP1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL3721184 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL8420644 | 0.80 | APLNR (0.44) | ALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL13258015 | 0.79 | ALDH1A1 (0.41) | ALDH1A1POLBKMT2APARP10BRD4 | |
| SCHEMBL3719649 | 0.79 | EPHX2 (0.42) | ALDH1A1KDM4EHPGDPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127212-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | SARMA PAKALA KUMARA SAVITHRU | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280067-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | ACACA, ACACB, PC | ALDH1A1 276/4885KDM4E 1375/4885HPGD 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.