Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456629 | 0.81 | MTNR1A (0.44) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL360947 | 0.80 | MTNR1B (0.50) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL6310248 | 0.78 | ALDH1A1 (0.51) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL6310241 | 0.78 | ALDH1A1 (0.51) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL20978627 | 0.77 | MTNR1A (0.60) | MTNR1BMTNR1AALDH1A1NPSR1TSHR | |
| SCHEMBL8405200 | 0.77 | MTNR1B (0.52) | MTNR1BMTNR1AALDH1A1MAPTKDM4E | |
| SCHEMBL27937262 | 0.76 | MTNR1A (0.56) | MTNR1BMTNR1A | |
| SCHEMBL16659181 | 0.76 | MTNR1B (0.42) | HTR2CHTR2AHTR2BMTNR1BMTNR1A | |
| SCHEMBL14405818 | 0.74 | MTNR1B (0.50) | MTNR1BMTNR1AEEDSUZ12EZH2 | |
| SCHEMBL13818785 | 0.72 | EED (0.44) | HTR2CHTR2AHTR2BMTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11147813-B2 | Modulators of KV3 channels to treat pain | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-10-19 | — | — | US | disclosed |
| US-9669030-B2 | Hydantoin derivatives as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11147813-B2 | Modulators of KV3 channels to treat pain | KCNN3, KCNA3, KCND3 | HTR2C 919/4885HTR2A 1395/4885HTR2B 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.