Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | TNKS | O95271 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18922767 | 0.91 | ABCB1 (0.69) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL24951027 | 0.84 | ABCB1 (0.64) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Chrysin Dimethyl Ether SCHEMBL29403280 | 0.82 | ABCG2 (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Chrysin Dimethyl Ether SCHEMBL1676012 | 0.82 | ABCG2 (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Methoxyvone SCHEMBL3409370 | 0.82 | CYP3A4 (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Methoxyvone SCHEMBL29373562 | 0.82 | CYP3A4 (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Techtochrysin SCHEMBL29494561 | 0.81 | MAPT (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| Techtochrysin SCHEMBL249043 | 0.81 | MAPT (1.00) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL16623939 | 0.78 | ALDH1A1 (0.66) | ABCG2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL4051739 | 0.76 | KDM4E (0.78) | ABCG2CYP3A4KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669066-B2 | Use of kaempferia parviflora wall. ex. baker extracts or flavone compound for preventing or treating muscle diseases, or improving muscle function | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2017-06-06 | — | — | US | disclosed |