Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16328356 | 0.97 | FAAH (0.42) | FAAHDNM1CASP2LMNAGAA | |
| SCHEMBL13880497 | 0.87 | CASP2 (0.36) | FAAHDNM1CASP2LMNANAAA | |
| SCHEMBL8166415 | 0.86 | FAAH (0.49) | FAAHDNM1GAAEPHX2HSD17B10 | |
| SCHEMBL12809270 | 0.86 | FAAH (0.34) | FAAHDNM1LMNAGAAEPHX2 | |
| SCHEMBL17278728 | 0.86 | EPHX2 (0.58) | KDM4EEPHX2TRPV1MEN1MAPT | |
| SCHEMBL15896251 | 0.84 | NOD1 (0.50) | — | |
| SCHEMBL8970617 | 0.84 | CASP2 (0.53) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL13260812 | 0.84 | SMN1; SMN2 (0.40) | FAAHLMNAGAA | |
| SCHEMBL13892164 | 0.83 | FAAH (0.38) | FAAHDNM1CASP2NAAAEPHX2 | |
| SCHEMBL16093010 | 0.82 | CASP2 (0.40) | FAAHDNM1CASP2NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670261-B2 | Functionalized exendin-4 derivatives | SANOFI (FR) | 2017-06-06 | — | — | US | disclosed |