Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17278728 | 0.85 | EPHX2 (0.58) | HPGDEPHX2SLC6A5MEN1ALDH1A1 | |
| SCHEMBL18923937 | 0.84 | FAAH (0.42) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL16328356 | 0.83 | FAAH (0.42) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL16093010 | 0.82 | CASP2 (0.40) | CASP2NAAAHPGDFAAHDNM1 | |
| SCHEMBL13113625 | 0.82 | CASP2 (0.40) | CASP2NAAAHPGDFAAHDNM1 | |
| SCHEMBL13880497 | 0.81 | CASP2 (0.36) | CASP2NAAAFAAHDNM1EPHX2 | |
| SCHEMBL13266983 | 0.80 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12999629 | 0.80 | ECE1 (0.40) | FAAH | |
| SCHEMBL13192595 | 0.78 | EPHX2 (0.64) | EPHX2 | |
| SCHEMBL12989767 | 0.78 | EPHX2 (0.64) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698016-A1 | NOVEL LUPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026725-A1 | NOVEL LUPANE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1994-11-24 | — | — | WO | disclosed |