SCHEMBL1892399

SCHEMBL1892399

CCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(C(=O)O)(C(=O)OC1CC(C)(C)N(C)C(C)(C)C1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.34
GAA P10253 2/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1768973 0.92 HMGCR (0.36) HMGCRGAAPKMHTTKMT2A
SCHEMBL6047482 0.88 HMGCR (0.36) HMGCRGAAPKMHTTKMT2A
SCHEMBL2546589 0.78 HMGCR (0.35) HMGCRGAAPKMHTTKMT2A
SCHEMBL2546593 0.78 GAA (0.38) HMGCRGAAPKMHTTKMT2A
SCHEMBL6875064 0.77 GAA (0.36) HMGCRGAAPKMHTTKMT2A
SCHEMBL10000628 0.76 GAA (0.39) HMGCRGAAPKMHTTKMT2A
SCHEMBL697946 0.76 HMGCR (0.36) HMGCRGAAPKMHTTKMT2A
SCHEMBL12933650 0.76 GAA (0.38) HMGCRGAAPKMHTTKMT2A
SCHEMBL2687904 0.75 GAA (0.40) HMGCRGAAPKMHTTKMT2A
SCHEMBL29013340 0.75 GAA (0.34) HMGCRGAAPKMHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4090710-B1 COATING COMPOSITIONS GKN AEROSPACE SERVICES LTD (GB) 2025-01-01 EP claimed
US-20230066264-A1 COATING COMPOSITIONS GKN AEROSPACE SERVICES LIMITED (GB) 2023-03-02 US claimed
US-11505675-B2 Polycarbonate resin compositions with consistent color and stable blue-cut performance ESSILOR INTERNATIONAL (FR) 2022-11-22 US claimed
EP-3296351-B1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE ESSILOR INT (FR) 2022-06-29 EP claimed
WO-2021146264-A1 COATING COMPOSITIONS GKN AEROSPACE SERVICES LIMITED (GB) 2021-07-22 WO claimed
US-20190264003-A1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE ESSILOR INTERNATIONAL (FR) 2019-08-29 US claimed
US-10208201-B2 Plastics composition comprising at least one metal pigment, method for production and use thereof ECKART GMBH (DE) 2019-02-19 US claimed
WO-2018055010-A1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE ESSILOR INTERNATIONAL (FR) 2018-03-29 WO claimed
EP-3296351-A1 POLYCARBONATE RESIN COMPOSITIONS WITH CONSISTENT COLOR AND STABLE BLUE-CUT PERFORMANCE Essilor International (FR) 2018-03-21 EP claimed
US-20160237275-A1 Plastics Composition Comprising at least One Metal Pigment, Method for Production and Use Thereof ECKART GMBH (DE) 2016-08-18 US claimed
US-9169373-B2 Method for preparing a thermoplastic polyurethane of improved yellowness index, and optical articles made therefrom Essilor International (Compagnie Générale d'Optique) (FR) 2015-10-27 US claimed
US-9163133-B2 Method of converting a polymerizable composition into thermoplastic polyurethane of improved yellowness index and article obtained by this method Essilor International (Compagnie Générale d'Optique) (FR) 2015-10-20 US claimed
US-20150252202-A1 RADIATION CURABLE INK COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-10 US claimed
US-20130201441-A1 METHOD FOR PREPARING A THERMOPLASTIC POLYURETHANE OF IMPROVED YELLOWNESS INDEX, AND OPTICAL ARTICLES MADE THEREFROM ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2013-08-08 US claimed
US-20130189720-A1 HIGH ENERGY RADIATION INSENSITIVE ANALYTE SENSORS EDWARDS LLIFESCIENCES CORPORATION (US) 2013-07-25 US claimed
US-20130158156-A1 METHOD OF CONVERTING A POLYMERIZABLE COMPOSITION INTO THERMOPLASTIC POLYURETHANE OF IMPROVED YELLOWNESS INDEX AND ARTICLE OBTAINED BY THIS METHOD ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) 2013-06-20 US claimed
US-20110115108-A1 PHOTOCHROMIC COATING EXHIBITING IMPROVED PERFORMANCE AND REDUCED YELLOWNESS ESSILOR INTERNATIONAL (FR) 2011-05-19 US claimed
EP-3405520-B1 POLYAMIDE COMPOSITION CONTAINING A METALLIC PIGMENT TICONA LLC (US) 2026-02-25 EP disclosed
EP-0512951-B1 Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers CIBA GEIGY AG (CH) 1997-07-23 EP disclosed
EP-0512951-A1 Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed