Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345179 | 0.84 | IDH1 (0.33) | GAAPKMHTTKMT2AMEN1 | |
| SCHEMBL9157712 | 0.80 | GAA (0.36) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL1768973 | 0.80 | HMGCR (0.36) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL1892399 | 0.78 | HMGCR (0.34) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL537219 | 0.78 | GAA (0.35) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL9784228 | 0.77 | GPR55 (0.32) | GAAPKMHTTKMT2AMEN1 | |
| SCHEMBL2546593 | 0.75 | GAA (0.38) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL6875064 | 0.75 | GAA (0.36) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL697946 | 0.74 | HMGCR (0.36) | HMGCRGAAPKMHTTKMT2A | |
| SCHEMBL28556085 | 0.73 | ALDH1A1 (0.43) | GAAPKMHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953595-A1 | UV light stabilized polyester molding composition | HOECHST CELANESE CORPORATION (US) | 1999-11-03 | — | — | EP | claimed |
| US-5025048-A | Oxygen resistant, storage-stable curable polysiloxanes hydrosilated by a polycyclic polyene and a compound containing an amine and a hydroxy, both sterically hindered | HERCULES INCORPORATED (US) | 1991-06-18 | — | — | US | claimed |
| EP-2121111-B1 | APPLICATORS FOR MICRONEEDLE ARRAYS | CORIUM INT INC (US) | 2018-03-14 | — | — | EP | disclosed |
| US-9259504-B2 | Non-electrically conductive hydrogel composition | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences (RU) | 2016-02-16 | — | — | US | disclosed |
| US-9242021-B2 | Adhesive composition | CORIUM INTERNATIONAL, INC. (US) | 2016-01-26 | — | — | US | disclosed |
| US-8821446-B2 | Applicators for microneedles | CORIUM INTERNATIONAL, INC. (US) | 2014-09-02 | — | — | US | disclosed |
| US-8821901-B2 | Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS RUSSIAN ACADEMY OF SCIENCES (RU) | 2014-09-02 | — | — | US | disclosed |
| US-8753669-B2 | Two-phase, water-absorbent bioadhesive composition | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (RU) | 2014-06-17 | — | — | US | disclosed |
| US-8728445-B2 | Hydrogel Compositions | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (RU) | 2014-05-20 | — | — | US | disclosed |
| US-20130261526-A1 | HYDROGEL COMPOSITIONS | CORIUM INTERNATIONAL, INC. (US) | 2013-10-03 | — | — | US | disclosed |
| US-8481059-B2 | Hydrogel compositions | A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (RU) | 2013-07-09 | — | — | US | disclosed |
| US-5298536-A | Residues of one silicon-containing compound and at least one polycylic polyene compound linked through carbon-silicon bond | HERCULES INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |
| US-5254655-A | Made by hydrosilation of cyclic polysiloxanes and carbon-carbon bond-containing dye | HERCULES INCORPORATED (US) | 1993-10-19 | — | — | US | disclosed |
| US-5242979-A | ORGANOSILICON COMPOSITIONS CONTAINING HYDROCARBON ELASTOMERS | HERCULES INCORPORATED (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0556844-A2 | Flame retardant organosilicon polymer composition, process for making same, and article produced therefrom | HERCULES INCORPORATED (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0554904-A2 | Organosilicon polymers, and dyes, exhibiting nonlinear optical response | HERCULES INCORPORATED (US) | 1993-08-11 | — | — | EP | disclosed |
| EP-0534206-A1 | Organosilicon polymers | HERCULES INCORPORATED (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5171817-A | Containing polycyclic polyenes | HERCULES INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-5025048-A | Oxygen resistant, storage-stable curable polysiloxanes hydrosilated by a polycyclic polyene and a compound containing an amine and a hydroxy, both sterically hindered | HERCULES INCORPORATED (US) | 1991-06-18 | — | — | US | disclosed |
| US-5008360-A | Organosilicon materials | HERCULES INCORPORATED (US) | 1991-04-16 | — | — | US | disclosed |