Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924221 | 0.89 | PTGS1 (0.50) | PTGS1GSTK1BMP1FNTAFNTB | |
| SCHEMBL19774705 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL24829528 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL18383664 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL22300031 | 0.87 | PTGS1 (0.47) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL26819626 | 0.82 | PTGS1 (0.62) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL25861362 | 0.81 | PTGS1 (0.48) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL26483467 | 0.81 | PTGS1 (0.60) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL21153272 | 0.80 | PTGS1 (0.44) | PTGS1GSTK1BMP1ACEMAPT | |
| SCHEMBL15700548 | 0.80 | PTGS1 (0.78) | PTGS1GSTK1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669016-B2 | Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-06 | — | — | US | disclosed |