Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924223 | 0.89 | PTGS1 (0.52) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL18383664 | 0.86 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL24829528 | 0.86 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL19774705 | 0.86 | GSTK1 (0.65) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL26819626 | 0.83 | PTGS1 (0.62) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL25861362 | 0.79 | PTGS1 (0.48) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL26483467 | 0.79 | PTGS1 (0.60) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL25861459 | 0.77 | PTGS1 (0.58) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL22300031 | 0.76 | PTGS1 (0.47) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL14781467 | 0.74 | PTGS1 (0.66) | PTGS1GSTK1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669016-B2 | Antiparasitic effect of Bis[3,5-Bis(Benzylidene)-4-Oxo-1-Piperidinyl]amide Derivatives | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-06 | — | — | US | disclosed |