Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383664 | 0.89 | GSTK1 (0.65) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL24829528 | 0.89 | GSTK1 (0.65) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL19774705 | 0.89 | GSTK1 (0.65) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL26819626 | 0.87 | PTGS1 (0.62) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL25861459 | 0.86 | PTGS1 (0.58) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL14781467 | 0.84 | PTGS1 (0.66) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL18924223 | 0.81 | PTGS1 (0.52) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL17287153 | 0.80 | PTGS1 (0.57) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL4424322 | 0.79 | MAPT (0.60) | PTGS1GSTK1GLO1MAPTALDH1A1 | |
| SCHEMBL18263621 | 0.79 | MAPT (0.60) | PTGS1GSTK1GLO1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191953-A1 | PNICTOGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2023-10-05 | — | — | WO | disclosed |