Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19822051 | 0.83 | LNPEP (0.37) | LNPEPNOS3NOS1NOS2LOX | |
| SCHEMBL21686484 | 0.81 | KDM4E (0.41) | LNPEPCYP1A2ALDH1A1CYP2C19NOS3 | |
| SCHEMBL6560519 | 0.80 | GABRA1 (0.42) | LNPEPCYP1A2ALDH1A1CYP2C19NOS3 | |
| SCHEMBL30846842 | 0.79 | LNPEP (0.34) | LNPEPCYP1A2ALDH1A1CYP2C19NOS3 | |
| SCHEMBL27209025 | 0.79 | LNPEP (0.34) | LNPEPCYP1A2ALDH1A1CYP2C19NOS3 | |
| SCHEMBL20207667 | 0.77 | NOS3 (0.52) | LNPEPCYP1A2ALDH1A1NOS3NOS1 | |
| SCHEMBL18924365 | 0.77 | KDM4E (0.35) | CYP1A2NOS3NOS1NOS2LOX | |
| SCHEMBL24294452 | 0.76 | LNPEP (0.35) | LNPEP | |
| SCHEMBL18924522 | 0.75 | LNPEP (0.43) | LNPEPKDM4E | |
| SCHEMBL9917323 | 0.75 | UHRF1 (0.43) | NOS3NOS1NOS2LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |