Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560519 | 0.88 | GABRA1 (0.42) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL25639311 | 0.85 | NOS3 (0.48) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL21686484 | 0.85 | KDM4E (0.41) | NOS3NOS1NOS2CYP1A2KDM4E | |
| SCHEMBL17000195 | 0.84 | POLB (0.44) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL21667315 | 0.81 | PNMT (0.46) | SLC6A2CYP2A6 | |
| SCHEMBL218290 | 0.81 | NOS3 (0.61) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL30846842 | 0.79 | LNPEP (0.34) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL19822051 | 0.79 | LNPEP (0.37) | NOS3NOS1NOS2POLBKDM4E | |
| SCHEMBL27209025 | 0.79 | LNPEP (0.34) | NOS3NOS1NOS2POLBCYP1A2 | |
| SCHEMBL11563922 | 0.79 | NOS3 (0.59) | NOS3NOS1NOS2POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |