Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924391 | 0.87 | POLB (0.45) | FASNS1PR1NPC1RAB9AHPGD | |
| SCHEMBL18924564 | 0.83 | FASN (0.68) | FASNS1PR1MTORNPC1RAB9A | |
| SCHEMBL16323792 | 0.82 | FASN (0.76) | FASN | |
| SCHEMBL18924349 | 0.76 | ABL1 (0.47) | FASNS1PR1MTORNPC1RAB9A | |
| SCHEMBL18924458 | 0.74 | DYRK1A (0.52) | FASNS1PR1MTORNPC1RAB9A | |
| SCHEMBL18924536 | 0.73 | S1PR1 (0.43) | FASNS1PR1MTORNPC1RAB9A | |
| SCHEMBL7880071 | 0.72 | S1PR1 (0.57) | S1PR1MTORNPC1RAB9AHPGD | |
| SCHEMBL13555906 | 0.71 | MCHR1 (0.50) | S1PR1MTORNPC1RAB9AMCHR1 | |
| SCHEMBL18924451 | 0.71 | MAPK14 (0.48) | FASNS1PR1NPC1RAB9AHPGD | |
| SCHEMBL20460410 | 0.70 | ALDH1A1 (0.47) | S1PR1MTORNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670142-B2 | 1,3-diaminocyclopentane carboxamide derivatives | MERCK PATENT GMBH (DE) | 2017-06-06 | — | — | US | disclosed |