Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924478 | 0.87 | KDM4E (0.50) | KDM4ECYP3A4LMNATSHRL3MBTL1 | |
| SCHEMBL18924522 | 0.87 | LNPEP (0.43) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL1328611 | 0.85 | LNPEP (0.48) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL28244414 | 0.84 | KCNH2 (0.50) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL2553622 | 0.84 | CYP3A4 (0.46) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL29058198 | 0.84 | KCNH2 (0.50) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL27345656 | 0.84 | KCNH2 (0.50) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL2550616 | 0.84 | NOS3 (0.50) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL31280277 | 0.84 | NOS3 (0.50) | LNPEPKCNH2KDM4ECYP3A4LMNA | |
| SCHEMBL2555694 | 0.82 | KCNH2 (0.48) | LNPEPKCNH2KDM4ECYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649222-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2023-05-16 | — | — | US | disclosed |
| US-10961223-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2021-03-30 | — | — | US | disclosed |
| US-20190284167-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2019-09-19 | — | — | US | disclosed |
| US-9670172-B2 | Heterocyclic compounds and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649222-B2 | Compounds | SLC30A6, SLC39A11, SLC39A3 | LNPEP 117/4885KCNH2 648/4885KDM4E 2941/4885 |
| US-10961223-B2 | Compounds | SLC30A6, SLC39A11, SLC30A5 | LNPEP 119/4885KCNH2 469/4885KDM4E 2847/4885 |
| US-20190284167-A1 | COMPOUNDS | SLC30A6, SLC39A11, SLC30A5 | LNPEP 119/4885KCNH2 469/4885KDM4E 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.