Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555694 | 0.98 | KCNH2 (0.48) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL1328611 | 0.94 | LNPEP (0.48) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL2554060 | 0.94 | KDM4E (0.47) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL29058198 | 0.92 | KCNH2 (0.50) | CYP3A4KDM4ELMNAKCNH2LNPEP | |
| SCHEMBL28244414 | 0.92 | KCNH2 (0.50) | CYP3A4KDM4ELMNAKCNH2LNPEP | |
| SCHEMBL16544526 | 0.92 | CYP3A4 (0.50) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL27345656 | 0.92 | KCNH2 (0.50) | CYP3A4KDM4ELMNAKCNH2LNPEP | |
| SCHEMBL2550616 | 0.89 | NOS3 (0.50) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL31280277 | 0.89 | NOS3 (0.50) | CYP3A4KDM4ELMNATSHRKCNH2 | |
| SCHEMBL6560564 | 0.88 | KDM4E (0.44) | CYP3A4KDM4ELMNATSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240390544-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2024-11-28 | — | — | US | claimed |
| EP-3648763-B1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH & CIE (CH) | 2022-11-30 | — | — | EP | claimed |
| US-20210145998-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2021-05-20 | — | — | US | claimed |
| EP-3648763-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | Firmenich SA (CH) | 2020-05-13 | — | — | EP | claimed |
| WO-2019008089-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2019-01-10 | — | — | WO | claimed |
| CN-102802600-B | As 2,4-disubstituted pyridines of perfuming component | FIRMENICH S.A. (CH) | 2016-04-13 | — | — | CN | claimed |
| US-8652452-B2 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH SA (CH) | 2014-02-18 | — | — | US | claimed |
| EP-2552395-B1 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH & CIE (CH) | 2013-11-13 | — | — | EP | claimed |
| EP-2552395-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2013-02-06 | — | — | EP | claimed |
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2013-01-03 | — | — | US | claimed |
| WO-2011121469-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2011-10-06 | — | — | WO | claimed |
| US-20240390544-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2024-11-28 | — | — | US | disclosed |
| US-12048783-B2 | 2,4-disubstituted pyridines as malodor counteracting ingredients | FIRMENICH SA (CH) | 2024-07-30 | — | — | US | disclosed |
| EP-3648763-B1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH & CIE (CH) | 2022-11-30 | — | — | EP | disclosed |
| US-20210145998-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | FIRMENICH SA (CH) | 2021-05-20 | — | — | US | disclosed |
| US-8652452-B2 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH SA (CH) | 2014-02-18 | — | — | US | disclosed |
| EP-2552395-B1 | 2,4-disubstituted pyridines as perfuming ingredients | FIRMENICH & CIE (CH) | 2013-11-13 | — | — | EP | disclosed |
| EP-2552395-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | Firmenich S.A. (CH) | 2013-02-06 | — | — | EP | disclosed |
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2013-01-03 | — | — | US | disclosed |
| WO-2011121469-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | FIRMENICH SA (CH) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004447-A1 | 2,4-DISUBSTITUTED PYRIDINES AS PERFUMING INGREDIENTS | P2RX5, P2RX4, C5 | CYP3A4 185/4885KDM4E 2458/4885LMNA 3310/4885 |
| US-20210145998-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | TAS2R4, P2RY4, QDPR | CYP3A4 86/4885KDM4E 947/4885LMNA 4822/4885 |
| US-12048783-B2 | 2,4-disubstituted pyridines as malodor counteracting ingredients | TAS2R4, P2RY4, QDPR | CYP3A4 86/4885KDM4E 947/4885LMNA 4822/4885 |
| US-20240390544-A1 | 2,4-DISUBSTITUTED PYRIDINES AS MALODOR COUNTERACTING INGREDIENTS | TAS2R4, LPO, PRDX4 | CYP3A4 145/4885KDM4E 1768/4885LMNA 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.