Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804031 | 0.73 | — | — | |
| SCHEMBL20180713 | 0.73 | LMNA (0.43) | LMNAMCL1POLBKDM4EKDM5C | |
| SCHEMBL22278102 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL22769249 | 0.71 | — | — | |
| SCHEMBL3660629 | 0.71 | LMNA (0.63) | LMNAMCL1POLBKDM4EKDM5C | |
| SCHEMBL23948507 | 0.68 | LMNA (0.39) | LMNAMCL1POLBTDP1 | |
| SCHEMBL8689460 | 0.68 | LMNA (0.39) | LMNAMCL1POLBTDP1ALDH1A1 | |
| SCHEMBL22278284 | 0.68 | KDM4E (0.33) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL20708377 | 0.68 | LMNA (0.39) | LMNAMCL1POLBKDM4ETDP1 | |
| SCHEMBL23789761 | 0.68 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | LMNA 2380/4885MCL1 56/4885POLB 3903/4885 |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | LMNA 1485/4885MCL1 20/4885POLB 3050/4885 |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | LMNA 2180/4885MCL1 36/4885POLB 3755/4885 |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | LMNA 2180/4885MCL1 36/4885POLB 3755/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | LMNA 2180/4885MCL1 36/4885POLB 3755/4885 |
| US-11834406-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | LMNA 2250/4885MCL1 46/4885POLB 3794/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | LMNA 493/4885MCL1 66/4885POLB 2693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.