Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23948566 | 0.81 | ALDH1A1 (0.38) | LMNATDP1 | |
| SCHEMBL18925533 | 0.68 | LMNA (0.43) | LMNAPOLBTDP1MCL1 | |
| SCHEMBL20180713 | 0.68 | LMNA (0.43) | LMNAPOLBTDP1MCL1 | |
| SCHEMBL3660629 | 0.67 | LMNA (0.63) | LMNAPOLBTDP1MCL1 | |
| SCHEMBL23948493 | 0.65 | SLC6A5 (0.46) | LMNA | |
| SCHEMBL8689460 | 0.64 | LMNA (0.39) | LMNAPOLBTDP1CYP1A2CYP2C9 | |
| SCHEMBL20708377 | 0.64 | LMNA (0.39) | LMNAPOLBTDP1MCL1 | |
| SCHEMBL93970 | 0.63 | — | — | |
| SCHEMBL5909180 | 0.62 | LMNA (0.57) | LMNAPOLBMCL1 | |
| SCHEMBL7753090 | 0.62 | LMNA (0.57) | LMNAPOLBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021211984-A1 | DIELS-ALDER CONJUGATION METHODS | REGENERON PHARMACEUTICALS, INC. (US) | 2021-10-21 | — | — | WO | disclosed |