Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835158 | 0.78 | — | — | |
| SCHEMBL17319497 | 0.73 | — | — | |
| SCHEMBL18925533 | 0.73 | LMNA (0.43) | LMNAMCL1POLBKDM4EKDM5C | |
| SCHEMBL3660629 | 0.71 | LMNA (0.63) | LMNAMCL1POLBKDM4EKDM5C | |
| SCHEMBL16579442 | 0.69 | CASP2 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL23948507 | 0.68 | LMNA (0.39) | LMNAMCL1POLBTDP1 | |
| SCHEMBL8689460 | 0.68 | LMNA (0.39) | LMNAMCL1POLBTDP1ALDH1A1 | |
| SCHEMBL20708377 | 0.68 | LMNA (0.39) | LMNAMCL1POLBKDM4ETDP1 | |
| SCHEMBL21788681 | 0.67 | FTO (0.38) | LMNAMCL1 | |
| SCHEMBL93970 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| US-10327423-B2 | Antimicrobial compounds and compositions, and uses thereof | Akeso Biomedical, Inc. (US) | 2019-06-25 | — | — | US | disclosed |
| US-10264766-B2 | Antimicrobial compounds and compositions, and uses thereof | Akeso Biomedical, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180139932-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | Akeso Biomedical, Inc. | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180139932-A1 | ANTIMICROBIAL COMPOUNDS AND COMPOSITIONS, AND USES THEREOF | TYR, TH, DDC | LMNA 4847/4885MCL1 2140/4885POLB 1637/4885 |
| US-10264766-B2 | Antimicrobial compounds and compositions, and uses thereof | TYR, TH, DDC | LMNA 4843/4885MCL1 2134/4885POLB 1663/4885 |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | LMNA 2180/4885MCL1 36/4885POLB 3755/4885 |
| US-10327423-B2 | Antimicrobial compounds and compositions, and uses thereof | TYR, TH, DDC | LMNA 4843/4885MCL1 2134/4885POLB 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.