SCHEMBL18927765

SCHEMBL18927765

Brc1ccc2sc3cc(N(c4ccccc4)c4ccccc4)ccc3c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN22 Q9Y2R2 2/20 0.40
▸ EPM2A O95278 1/20 0.40
▸ PTPN2 P17706 1/20 0.40
▸ PTPN1 P18031 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.37
▸ MAPT P10636 3/20 0.37
▸ HPGD P15428 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ GPR3 P46089 1/20 0.34
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18927685 0.96 MAPT (0.41) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927679 0.94 ALDH1A1 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927796 0.94 PTPN22 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927800 0.92 ALDH1A1 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL13242813 0.92 EPM2A (0.42) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927687 0.91 ALDH1A1 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL6134748 0.90 APP (0.35) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927670 0.90 PTPN22 (0.36) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL23358147 0.89 MAPT (0.45) PTPN22ALDH1A1MAPTHPGDRAB9A
SCHEMBL30844884 0.89 MAPT (0.45) PTPN22ALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
WO-2017217654-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2017-12-21 — — WO disclosed
WO-2017095075-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2017-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE OR10J3, OR51E2, ORAI2 PTPN22 3111/4885EPM2A 1238/4885PTPN2 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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