SCHEMBL18927796

SCHEMBL18927796

Brc1ccc2c(c1)sc1ccc(N(c3ccccc3)c3ccccc3)cc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN22 Q9Y2R2 2/20 0.37
▸ EPM2A O95278 1/20 0.37
▸ PTPN2 P17706 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ ALDH1A1 P00352 4/20 0.37
▸ MAPT P10636 4/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ GPR3 P46089 1/20 0.34
▸ L3MBTL1 Q9Y468 3/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ APP P05067 2/20 0.31
▸ EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6134748 0.96 APP (0.35) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927878 0.94 ALDH1A1 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927765 0.94 PTPN22 (0.40) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927685 0.93 MAPT (0.41) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL13242813 0.92 EPM2A (0.42) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18927800 0.92 ALDH1A1 (0.37) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL25492397 0.91 ALDH1A1 (0.34) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL18928070 0.90 PIM3 (0.36) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL25492395 0.90 EPM2A (0.32) PTPN22EPM2APTPN2PTPN1ALDH1A1
SCHEMBL14926289 0.89 GPR3 (0.44) PTPN22EPM2APTPN2PTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
WO-2019172623-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-09-12 — — WO disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 — — US disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 — — US disclosed
WO-2017095075-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2017-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF OCIAD1, GPX1, PIEZO1 PTPN22 2871/4885EPM2A 644/4885PTPN2 3056/4885
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE OR10J3, OR51E2, ORAI2 PTPN22 3111/4885EPM2A 1238/4885PTPN2 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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