SCHEMBL18927685

SCHEMBL18927685

Brc1ccc2sc3cc(N(c4ccccc4)c4ccc5sc6ccccc6c5c4)ccc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ HPGD P15428 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ GPR3 P46089 1/20 0.39
▸ PTPN22 Q9Y2R2 2/20 0.37
▸ EPM2A O95278 1/20 0.37
▸ PTPN2 P17706 1/20 0.37
▸ PTPN1 P18031 1/20 0.37
▸ CYP1A2 P05177 2/20 0.35
▸ PTPN7 P35236 1/20 0.34
▸ DUSP3 P51452 1/20 0.34
▸ PTPN12 Q05209 1/20 0.34
▸ MAOA P21397 1/20 0.34
▸ MAOB P27338 1/20 0.34
▸ TDP1 Q9NUW8 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18927765 0.96 PTPN22 (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL18927796 0.93 PTPN22 (0.37) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL18927687 0.92 ALDH1A1 (0.37) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL14926289 0.91 GPR3 (0.44) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL23358147 0.91 MAPT (0.45) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL30844884 0.91 MAPT (0.45) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL20201271 0.91 MAPT (0.47) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL21966423 0.91 MAPT (0.47) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL22355407 0.91 MAPT (0.47) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL20201278 0.91 MAPT (0.47) MAPTALDH1A1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE DUK SAN NEOLUX CO., LTD. (KR) 2023-05-18 — — US disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 — — US disclosed
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2017-10-05 — — US disclosed
WO-2017095075-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE 덕산네오룩스 주식회사 2017-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288148-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING THE SAME, AND ELECTRONIC DEVICE THEREOF OCIAD1, GPX1, PIEZO1 MAPT 2496/4885ALDH1A1 453/4885HPGD 3272/4885
US-20230157160-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE OR10J3, OR51E2, ORAI2 MAPT 1758/4885ALDH1A1 1082/4885HPGD 2154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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