Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321346 | 0.84 | PDE7A (0.55) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL24063592 | 0.81 | ALDH1A1 (0.53) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL11499701 | 0.81 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL3917921 | 0.78 | PDE7A (0.49) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL2458682 | 0.78 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL6860656 | 0.78 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL6870788 | 0.78 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL224666 | 0.77 | PDE7A (0.60) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL875772 | 0.77 | PDE7A (0.78) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL31272173 | 0.77 | PDE7A (0.78) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |