Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803017 | 0.81 | TRPV4 (0.56) | TRPV4KMT2ACYP19A1L3MBTL1TP53 | |
| SCHEMBL11449777 | 0.80 | ACHE (0.50) | KMT2AL3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL805037 | 0.80 | CA12 (0.50) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL12894420 | 0.79 | SMN1; SMN2 (0.38) | KMT2ATP53LMNAMEN1ALDH1A1 | |
| SCHEMBL21230582 | 0.79 | MAPT (0.50) | KMT2ACYP19A1TP53LMNAMEN1 | |
| SCHEMBL2955499 | 0.78 | CYP3A4 (0.47) | KMT2ATP53NR3C1NR3C2LMNA | |
| SCHEMBL16579380 | 0.78 | TRPV4 (0.49) | TRPV4KMT2ACYP19A1L3MBTL1TP53 | |
| SCHEMBL13763478 | 0.77 | CYP3A4 (0.54) | KMT2AL3MBTL1TP53LMNAMEN1 | |
| SCHEMBL27768786 | 0.77 | NR3C1 (0.50) | CYP19A1NR3C1NR3C2PGR | |
| Hydrochloric Acid SCHEMBL31409980 | 0.76 | TRPV4 (0.47) | TRPV4KMT2ACYP19A1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922841-B1 | ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES | BRISTOL MYERS SQUIBB CO (US) | 2017-06-07 | — | — | EP | disclosed |